Materials and methods
Guideline OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method) OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance yes (incl. QA statement) yes (incl. QA statement)
Species rat rat
Strain Wistar Han Wistar Han
Sex female female
Route of administration oral: gavage oral: gavage
Vehicle corn oil corn oil
Doses 300 and 2000 mg/kg bw 300 and 2000 mg/kg bw
Results and discussion
Dose descriptor LD50 cut-off LD50 cut-off
Effect level 500 mg/kg bw 500 mg/kg bw
Applicant’s summary and conclusion
Interpretation of results Category 4 based on GHS criteria Category 4 based on GHS criteria